| Retinal Nerve Fiber Layer and Macular Ganglion Cell Thicknesses in Situs Inversus of Optic Discs. |
|
Min Kyung Kim, Jae Min Kim, Young Hoon Hwang |
|
Myung-Gok Eye Research Institute, Department of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, Korea. brainh@hanmail.net |
| 시신경유두 좌우 뒤바뀜이 있는 눈의 망막신경섬유층 및 황반부 신경절세포 두께 |
|
김민경⋅김재민⋅황영훈 |
|
건양대학교 의과대학 김안과병원 안과학교실 명곡안연구소 |
Correspondence:
Young Hoon Hwang,
Email: brainh@hanmail.net
|
|
Received: 1 December 2016 • Revised: 10 January 2017 • Accepted: 16 March 2017 |
| Abstract |
PURPOSE
To investigate circumpapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer (GCIPL) thicknesses as measured by optical coherence tomography in eyes with situs inversus of optic discs. METHODS: RNFL and macular GCIPL thicknesses were measured in eyes with situs inversus of optic discs without other ocular abnormalities (situs inversus group) and in age- and refractive error-matched healthy eyes (control group). RNFL thickness (global area, superior, nasal, inferior, and temporal quadrants) and GCIPL thickness (global area, superior-temporal, superior, superior-nasal, inferior-nasal, inferior, and inferior-temporal sectors and minimum) were compared between the groups. RESULTS: Nine eyes of 5 subjects with situs inversus of optic discs and 20 healthy eyes of 20 subjects (10 eyes for control groups A and B, respectively) were enrolled. No significant difference was found in superior or inferior quadrant RNFL thickness (p > 0.05); however, the situs inversus group showed a thicker RNFL in the nasal quadrant and a thinner RNFL in the temporal quadrant (p < 0.01). In macular GCIPL thickness, no significant difference was found in the superotemporal or inferiotemporal sector or for minimum thickness (p < 0.05); however, the situs inversus group showed thicker GCIPL in the global area, superior, superonasal, inferonasal, and inferior sectors than the control groups (p < 0.01). CONCLUSIONS: In eyes with situs inversus of optic discs, distribution of circumpapillary RNFL and macular GCIPL thickness were different from eyes without this condition. When assessing RNFL and macular GCIPL thicknesses in eyes with situs inversus of optic discs, caution is needed. |
| Key Words:
Optic nerve head;Retinal ganglion cell;Retinal nerve fiber layer;Situs inversus |
|
PDF Links
Full text via DOI
Download Citation
