| Amoebicidal Effect of Nephrite-containing Contact Lens Storage Case. |
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Jae Woo Jung, Jong Heon Lee, Sung Hee Park, Hak Sun Yu, Yoon Kyung Kim, Ji Eun Lee |
1Department of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea. Jiel75@hanmail.net
2Department of Parasitology, Pusan National University School of Medicine, Yangsan, Korea.
3Department of Optometry, Busan Women's College, Busan, Korea.
4Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea. |
| 연옥이 첨가된 콘택트렌즈 보관용기의 항아메바 효과 |
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정재우1⋅이종헌1⋅박성희2⋅유학선2⋅김윤경3⋅이지은1,4 |
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부산대학교 의학전문대학원 양산부산대학교병원 안과학교실1, 부산대학교 의학전문대학원 기생충학교실2, 부산여자대학교 안경광학과3,부산대학교 의학전문대학원 양산부산대학교병원 의생명융합연구소4 |
Correspondence:
Ji-Eun Lee, MD, PhD
Email: Jiel75@hanmail.net |
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Received: 2 February 2017 • Revised: 28 February 2017 • Accepted: 18 April 2017 |
| Abstract |
PURPOSE
To compare the amoebicidal effects of nephrite containing contact lens (CL) storage cases with conventional CL storage cases. METHODS: Acanthamoeba lugdunensis were inoculated onto 5% nephrite containing CL storage cases as well as conventional CL storage cases both with and without silicone hydrogel contact lenses (SHCLs). Then the amount of Acanthamoeba proliferation on CL storage cases and the number of adherent Acanthamoeba on SHCLs were determined and compared. The effects of multipurpose solution (MPS) with and without 1% or 5% nephrite solution on Acanthamoeba adhesion were analyzed. RESULTS: Nephrite containing CL storage cases showed more inhibitory effects on Acanthamoeba proliferation (p = 0.02) and significantly reduced the number of adherent Acanthamoeba on SHCLs compared with conventional CL storage cases, regardless of SHCLs generation (p = 0.001, p = 0.001 and p < 0.001, respectively). The number of adherent Acanthamoeba on the first generation of SHCLs was significantly reduced by MPS with 1% and 5% nephrite solutions (p = 0.03 and p = 0.004, respectively), but the numbers for the second and third generation SHCLs were not. CONCLUSIONS: Nephrite could be used as a new additive component for CL storage cases and multipurpose solutions to improve the disinfection effects on Acanthamoeba. |
| Key Words:
Acanthamoeba;Contact lens storage case;Multipurpose solution;Nephrite |
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