| Primary Squamous Cell Carcinoma of the Orbit. |
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Da Ye Choi, Jung Hye Lee, Jung Hyun Ahn, Yeon Lim Suh, Kyung In Woo, Yoon Duck Kim |
1Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. Cdy8508@daum.net
2Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. |
| 안와 내에 발생한 원발성 편평상피세포암 1예 |
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최다예1⋅이정혜1⋅안정현1⋅서연림2⋅우경인1⋅김윤덕1 |
Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine1, Seoul, Korea
Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine2, Seoul, Korea |
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| Abstract |
PURPOSE
Normal squamous cells do not exist in the orbit. Therefore squamous cell carcinoma of the orbit is rare and usually arises as a secondary tumor from distant metastasis or local invasion. The authors herein describe the first case of primary squamous cell carcinoma of the orbit in Korea. CASE SUMMARY: A 74-year-old female presented with a 2-month history of left upper eyelid swelling and ocular pain. On physical examination, a round, firm, fixed and tender mass was palpable in the superomedial side of the left orbit. Magnetic resonance imaging (MRI) showed 21 mm x 15 mm x 20 mm-sized irregular soft tissue mass with indistinct margin and peripheral enhancement in the superomedial portion of the left orbit, and incisional biopsy of the mass was performed. Histopathological examination showed clusters of squamous cells with polymorphic nuclei and interspersed keratin pearls, consistent with findings of well-differentiated squamous cell carcinoma. Despite extensive systemic work-up, there was no sign of extraorbital malignancy. The patient received left exenteration and adjuvant radiation therapy. Ten months after enucleation, a 12 mm x 14 mm sized firm mass developed on the left forehead, and excisional biopsy and frontalis rotational flap reconstruction were performed. Histopathological examination of the mass was consistent with well-differentiated squamous cell carcinoma. The patient remained alive 17 months after diagnosis without evidence of local recurrence or distant metastasis. CONCLUSIONS: Primary squamous cell carcinoma should be considered in the differential diagnosis of acutely progressing tumors of the orbit. |
| Key Words:
Orbital;Primary;Squamous cell carcinoma |
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