J Korean Ophthalmol Soc > Volume 55(10); 2014 > Article
Journal of the Korean Ophthalmological Society 2014;55(10):1493-1498.
DOI: https://doi.org/10.3341/jkos.2014.55.10.1493    Published online October 15, 2014.
Macular Ischemia Correlated with Final Visual Outcome in Retinal Vein Occlusion Patients.
Gwang Myung Noh, Ji Eun Lee, Ki Yup Nam, Seung Uk Lee, Sang Joon Lee
Department of Ophthalmology, Kosin University College of Medicine, Busan, Korea. hhiatus@gmail.com
망막정맥폐쇄 환자에서 황반허혈과 최종시력과의 연관성
노광명⋅이지은⋅남기엽⋅이승욱⋅이상준
Department of Ophthalmology, Kosin University College of Medicine, Busan, Korea
Abstract
PURPOSE
To identify the correlation between final visual outcome after at least 6 months of follow-up and the extent of macular ischemia on the first visit. METHODS: We performed a retrospective clinical analysis of macular ischemia using clinical records, fundus examinations, and fluorescein angiographies in 83 patients (86 eyes) diagnosed with retinal vein occlusion from January 1998 to July 2012 and followed up for over 6 months. We evaluated the extent and the location of macular ischemia, macular edema, initial and final visual acuities and systemic disease based on fluorescein angiography and optical coherence tomography performed within 2 weeks of the first visit. The patients were divided into the following 4 groups based on the extent and location of macular ischemia and edema: superotemporal, superonasal, inferotemporal, and inferonasal. RESULTS: Retinal vein occlusions (RVOs) consisted of 24 central RVOs (CRVOs) and 62 branch RVOs (BRVOs). Mean initial acuity (log MAR) was 0.35 +/- 0.31 (36 eyes) in the no macular ischemia group, 0.40 +/- 0.21 (11 eyes) in the 1-quadrant macular ischemia group, 0.71 +/- 0.32 (26 eyes) in the 2-quadrant macular ischemia group and 0.73 +/- 0.36 (13 eyes) in the over 3 quadrants macular ischemia group. Mean final acuity (log MAR) was 0.23 +/- 0.23 in the no macular ischemia group, 0.40 +/- 0.30 in the 1-quadrant macular ischemia group, 0.51 +/- 0.32 in the 2-quadrant macular ischemic group and 0.73 +/- 0.31 in the over 3 quadrants macular ischemia group. CONCLUSIONS: The initial and final visual outcomes were worse when more quadrants were affected by macular ischemia. The extent of macular ischemia was correlated with initial visual acuity and final visual outcome but not with macular edema.
Key Words: Capillary nonperfusion;Macular ischemia;Retinal vein occlusion;Visual prognosis


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