Acute Retrobulbar Optic Neuritis with Hematologic Abnormalities.

Park, Si Yoon; Kang, Eun Min; Lee, Yun Ha; Kim, Chan Yun; Seong, Gong Je; Hong, Samin

doi:2014.55.10.1567

J Korean Ophthalmol Soc > Volume 55(10); 2014 > Article

Case Report

Journal of the Korean Ophthalmological Society 2014;55(10):1567-1572.
DOI: https://doi.org/10.3341/jkos.2014.55.10.1567 Published online October 15, 2014.

Acute Retrobulbar Optic Neuritis with Hematologic Abnormalities.

Si Yoon Park, Eun Min Kang, Yun Ha Lee, Chan Yun Kim, Gong Je Seong, Samin Hong

Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. samini@yuhs.ac

혈액학적 이상과 동반된 급성 구후시신경염

박시윤⋅강은민⋅이윤하⋅김찬윤⋅성공제⋅홍사민

Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea

Abstract

PURPOSE
We present a case of a patient with optic neuritis who had underlying suspicious idiopathic thrombocytopenic purpura. CASE SUMMARY: 35-year-old female with no other systemic disease visited our clinic due to acutely decreased visual acuity in her left eye 10 days in duration. Relative afferent pupillary defect was observed, but without definite papilledema. Based on brain magnetic resonance imaging (MRI), optic neuritis was suspected. Laboratory tests showed increased red blood cells, hemoglobin and, hematocrit levels and decreased platelets. Peripheral blood smear test showed decreased platelets, relative lymphocytosis and atypical lymphocytes. Specific antibodies for autoimmune disease were not present. High-dose steroid pulse therapy (methyl prednisolone 1.0 g/d, 3 days) was started. One month after treatment her visual acuity and platelet count recovered and her visual field defect improved.

Key Words: Autoimmune disease;Idiopathic thrombocytopenic purpura;Multiple sclerosis;Neuromyelitis optica;Optic neuritis