Association between Weight Gain and the Occurrence and Severity of Retinopathy of Prematurity. |
Ko Eun Kim, Jeong Hun Kim, Ee Kyung Kim, Han Suk Kim, Jung Hwan Choi, Young Suk Yu |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. ysyu@snu.ac.kr 2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea. 3Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea. |
미숙아망막병증의 발생 및 진행과 체중증가율과의 연관성에 관한 분석 |
김고은1⋅김정훈1,2⋅김이경3⋅김한석3⋅최중환3⋅유영석1,2 |
Department of Ophthalmology, Seoul National University College of Medicine1, Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute2, Department of Pediatrics, Seoul National University College of Medicine3, Seoul, Korea |
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Abstract |
PURPOSE To evaluate the association between the occurrence and severity of retinopathy of prematurity (ROP) and postnatal weight gain. METHODS: The medical records and mean rate of postnatal weekly weight gain measurements for 275 premature infants were retrospectively reviewed. According to fundus examination findings, 275 infants were divided into the following three groups according to the international classification of ROP: Group I; infants with no ROP, Group II; infants with mild ROP (stage 1 or stage 2 with no additional disease or spontaneous regression), and Group III; infants with moderate to severe ROP (stage 3, threshold or Type I ROP according to ET-ROP). The mean rates of postnatal weekly weight gain in each group were compared and other risk factors were evaluated. RESULTS: There was a tendency of decrement in the mean rate of postnatal weekly weight gain in association with the severity of the disease (Group I: 13.54 +/- 11.87%; Group II: 12.38 +/- 1.33%; Group III: 11.41 +/- 1.70%) but no statistical significance was found. Additionally, there was no statistically significant difference between the group without ROP and the group with ROP. Significant risk factors related to ROP were low birth weight, low gestational age, low Apgar score, long duration of oxygen therapy, high incidence of respiratory distress syndrome and bronchopulmonary dysplasia. CONCLUSIONS: The change in postnatal weight gain has limited usage as a main prognostic factor in predicting the progression of ROP. |
Key Words:
Postnatal weight gain;Retinopathy of prematurity |
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