J Korean Ophthalmol Soc > Volume 53(2); 2012 > Article
Journal of the Korean Ophthalmological Society 2012;53(2):256-261.
DOI: https://doi.org/10.3341/jkos.2012.53.2.256    Published online February 15, 2012.
The Effect of alpha1-Adrenergic Blocker on Phacoemulsification.
Eun Kyoung Kim, Sung Kun Chung, Nam Ho Baek
1Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine, Seoul, Korea.
2Department of Ophthalmology, Saevit Eye Hospital, Seoul, Korea. namhobaek@hotmail.com
알파1-교감신경길항제가 수정체유화술에 미치는 영향
김은경1⋅정성근1⋅백남호2
Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine1, Seoul, Korea Department of Ophthalmology, Saevit Eye Hospital2, Seoul, Korea
Abstract
PURPOSE
To evaluate the influence of alpha1-adrenergic blocker on phacoemulsification and the preventive effect of adrenergic blocker (AB) cessation before cataract surgery. METHODS: A prospective study was performed involving 92 eyes of 60 patients undergoing cataract surgery. Cases were divided into three groups: the use of alpha1AB with discontinuance before surgery (32 eyes), the use of alpha1AB with no discontinuance before surgery before surgery (31 eyes), and eyes not treated with alpha1AB (29 eyes). Clinical measurements and intraoperative parameters were compared among the three groups. RESULTS: Preoperative maximum pupil diameters of patients treated with alpha1AB were smaller than those of patients not administered alpha1AB (p = 0.027 and p = 0.018, respectively). The incidence of IFIS in the patients using of alpha1AB with discontinuance before surgery was 6.25%, and that in the patients using of alpha1AB with no discontinuance before surgery was 6.45%. There was no IFIS outbreak in the patients not using of alpha1AB. We noted no significant differences in absolute phaco time during phacoemulsification (p = 0.207) or in the three-month postoperative best corrected visual acuities among the three groups (p = 0.189). CONCLUSIONS: Importantly, there appears to be a significant correlation between alpha1AB and the development of IFIS. To prevent complications of IFIS, surgeons should be vigilant in identifying patients taking alpha1AB, checking the degree of preoperative pupil dilatation and anticipating intraoperative difficulties. In addition, appropriate modifications should be made to the surgical strategy. Furthermore there was no benefit to discontinuing alpha1AB treatment before cataract surgery in the prevention of IFIS.
Key Words: alpha1-adrenergic blocker;Intraoperative floppy iris syndrome;Phacoemulsification


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