| Multifocal Electroretinography in Retinitis Pigmentosa With Non-recordable Full-field Electroretinography. |
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Sun Young Jang, Sang Hyun Lim, Young Hoon Ohn |
1Department of Ophthalmology, Soonchunhyang University, College of Medicine, Bucheon, Korea. yhohn@schbc.ac.kr
2Department of Ophthalmology, University of California at San Francisco, Cornea Service, California, USA. |
| 전체시야망막전위도에서 무반응인 망막색소상피변성의 다국소망막전위도 |
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장선영1ㆍ임상현2ㆍ온영훈1 |
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Department of Ophthalmology, Soonchunhyang University, College of Medicine1, Bucheon, Korea, Department of Ophthalmology, University of California at San Francisco, Cornea Service2, California, USA |
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| Abstract |
PURPOSE
To investigate the clinical potential of multifocal electroretinography (mf-ERG) for the evaluation of residual retinal function in retinitis pigmentosa (RP). METHODS: From a group of 41 patients with RP examined for full-field and mf-ERGs, 24 patients were selected in whom the full-field ERGs were non-detectable. Data from the mf-ERGs of this group were reviewed retrospectively. Patients were divided into two groups based on best corrected visual acuity (BCVA); Group A, with a BCVA of less than 0.5, and group B with a BCVA greater than 0.5. The amplitudes and implicit times of Ring 1 and Ring 2 among six concentric rings were measured for comparison between mf-ERG groups. RESULTS: In the mf-ERGs, the amplitudes of Ring 1 and Ring 2 were reduced and implicit time was delayed in all 48 eyes of 24 patients in whom scotopic and photopic responses were non-detectable in full-field ERGs, whereas, there were no detectable responses in Rings 3 thru 6. There was a greater reduction in amplitude and an increased delay in implicit time in group A. CONCLUSIONS: The mf-ERG can estimate the residual macular function in a group of patients with RP in whom the full-field ERG is non-recordable. |
| Key Words:
Multifocal electroretinography (mfERG);Retinitis pigmentosa |
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