Effect of Simultaneous Intravitreal Bevacizumab and Retrobulbar Triamcinolone Injection in Refractory Neovascular Glaucoma. |
Woo Jin Kim, Jin Gu Jeong, In Cheon You, Dong Wook Lee |
Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea. ldw@chonbuk.ac.kr |
난치성 신생혈관 녹내장에서 유리체강내 베바시주맙과 구후 트리암시놀론 동시 주사 효과 |
김우진ㆍ정진구ㆍ유인천ㆍ이동욱 |
Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea |
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Abstract |
PURPOSE To identify the regression of neovascularization and relief of other symptoms after intravitreal bevacizumab and retrobulbar triamcinolone injection in neovascular glaucoma patients with no possibility of visual acuity recovery. METHODS: A total of 15 eyes in 15 patients with neovascular glaucoma, who had no possibility of visual acuity recovery and could not be treated with surgical intervention despite pain from October 2008 to May 2009, were reviewed retrospectively. Changes in degree of pain, conjunctival injection, revascularization, and visual acuity were evaluated after injection. RESULTS: Ten of the 15 (67%) neovascular glaucoma patients were male, with a mean age of 62.50+/-12.79 years. The most common prediposing ocular disease was diabetic retinopathy (9; 60%), and the others were central retinal vein occlusion (4: 26%), central retinal artery occlusion (1; 7%), and uveitis (1; 7%). Change in intraocular pressure was significant (p<0.001), as were decreases in the degrees of pain and conjunctival injection (p<0.001, <0.001) after the injections. Regression of neovascularization continued in 13 patients (87%) after two months. CONCLUSIONS: Intravitreal bevacizumab and retrobulbar triamcinolone injection is a safe intervention that can substantially relieve pain experienced by neovascular glaucoma patients. |
Key Words:
Bevacizumab;Neovascular glaucoma;Triamcinolone |
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