| The Amniotic Membrane Transplantation in Corneal Perforation due to Mooren's Ulcer. |
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Moon Jung Kim, Won Ryang Wee, Jin Hak Lee, Mee Kum Kim |
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea. kmk9@snu.ac.kr
2Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute, Seoul, Korea.
3Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul, Korea. |
| 각막 천공을 동반한 무렌각막궤양에 시행한 양막이식술 |
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김문정1,2,위원량1,2,이진학2,3,김미금1,2 |
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Department of Ophthalmology, Seoul National University College of Medicine1, Seoul, Korea Seoul Artificial Eye Center, Seoul National University Hospital Clinical Research Institute2, Seoul, Korea Department of Ophthalmology, Seoul National University Bundang Hospital3, Seoul, Korea |
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Correspondence:
Moon Jung Kim, M.D.1,2 |
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| Abstract |
PURPOSE
To report patients with corneal perforation with Mooren's ulcer treated successfully with amniotic membrane transplantation and cryotherapy. METHODS: We performed conjunctival recession, permanent amniotic membrane transplantation, cryotherapy, amniotic membrane patch to treat corneal perforation associated with severe inflammatory Mooren's ulcer of 4 eyes in 3 patients. We investigated the interval of absence of inflammation, reepithelization over grafted amniotic membrane, and restoration of visual acuity. RESULTS: The perforated corneal lesion was sealed successfully by the amniotic membrane in 4 eyes. The complete reepithelization over grafted amniotic membrane was achieved 21+/-2.7 days and complete remission was achieved 94+/-13.0 days after surgery. There was no recurrence in 3 eyes during 21+/-2.7 months. A patient who recurred inflammatory impending corneal perforation underwent limbal transplantation with amniotic membrane re-transplantation, which resulted in remission after 13 months. All 3 eyes restored visual acuity Except one who developed cataract. CONCLUSIONS: Amniotic membrane transplantation may be useful in treating corneal perforation with active inflammation in Mooren's ulcer. |
| Key Words:
Amniotic membrane transplantation;Corneal perforation;Mooren's ulcer;Reepithelialization |
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