Journal of the Korean Ophthalmological Society 2007;48(7):935-941.
Published online July 31, 2007.
Stratus OCT, SWAP, Matrix FDT in Preperimetric Glaucoma.
Soon Il Kwon, Yun Jeong Kim, Yun Seok Chung
Department of Ophthalmology, Hallym University Sacred Heart Hospital, College of Medicine, Gyeonggi, Korea. eyechung90@hallym.or.kr
시야결손 전 녹내장 환자의 광간섭단층촬영, 단파장시야측정, 주파수배가시야검사계 결과
권순일,김윤정,정윤석
Department of Ophthalmology, Hallym University Sacred Heart Hospital, College of Medicine, Gyeonggi, Korea
Correspondence:  정윤석
Abstract
PURPOSE
To evaluate the peripapillary retinal nerve fiber layer (RNFL) thickness with optical coherence tomography (OCT) in normal subjects and preperimetric glaucoma patients, as well as compare the results of OCT, short wavelength automated perimetry (SWAP), frequency doubling technology perimetry (FDT) in preperimetric glaucoma patients. METHODS: Thirty-six eyes of 36 preperimetric glaucoma patients who have definitive localized RNFL defects in disc photograph and normal standard visual field, as well as 35 eyes of 35 normal subjects, were enrolled in this study. We compared the peripapillary RNFL thickness between the two groups using Stratus OCT. Stratus OCT, FDT, and SWAP results in preperimetric glaucoma group were also compared. RESULTS: Compared with normal controls, peripapillary RNFL thickness, including the average, superior, and inferior quadrant, was significantly low (P<0.05) in the preperimetric glaucoma group, 93.40+/-11.16 micrometer, 118.33+/-21.17 micrometer, and 108.72+/-16.76 micrometer respectively. In preperimetric glaucoma group, functional and structural abnormalities were found in 55.6% with Stratus OCT, 31.4% with SWAP, and 79.4% with Matrix FDT. CONCLUSIONS: Statistically significant reduction of RNFL thickness was revealed in the preperimetric glaucoma group, and Matrix FDT was the most sensitive test for detecting early glaucomatous change, followed by Stratus OCT, and SWAP.
Key Words: Matrix FDT;Preperimetric glaucoma;Stratus OCT;SWAP


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