Journal of the Korean Ophthalmological Society 2004;45(10):1719-1723.
Published online October 1, 2004.
Changes of Higher Order Aberrations with the Use of Various Mydriatics.
Myoung Joon Kim, Jae Hyung Kim, Tae Hyung Lim, Hungwon Tchah
Department of Ophthalmology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea. hwtchah@amc.seoul.kr
산동제의 종류에 따른 고위 수차의 변화
김명준 ( Myoung Joon Kim ) , 김재형 ( Jae Hyung Kim ) , 임태형 ( Tae Hyung Lim ) , 차흥원 ( Hung Won Tchah )
Abstract
PURPOSE
To evaluate the changes of higher-order aberrations of the eye with the application of various mydriatics. METHODS: Higher-order aberrations were measured in 18 eyes of 11 subjects (ages 26 to 37 years; 9 males, 2 females) without any ocular diseases except refractive errors. Repeated measurements were conducted before and after instillation of 1 drop of three different mydriatics: 10% phenylephrine, a combination of 0.5% tropicamide and 0.5% phenylephrine (Mydrin(R)-P), and 1% cyclopentolate. The data from 6 mm pupil size were calculated and analyzed. RESULTS: Average root mean square of higher-order (HO-RMS) aberrations was 0.39 in undilated eyes. The averages HO-RMS after instillation of phenylephrine, Mydrin(R)-P, and cyclopentolate was 0.40, 0.41, and 0.42, respectively. There was no statistically significant difference among the four HO-RMS conditions. The spherical aberration of undilated or phenylephrine-instilled condition was different from that of Mydrin(R)-P or cyclopentolate condition (p<0.05). CONCLUSIONS: The application of mydriatics affected the higher-order aberrations of eyes. These findings should be considered when performing wavefront-guided refractive surgery.
Key Words: Aberration;Mydriatics;Spherical aberration


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