Journal of the Korean Ophthalmological Society 2003;44(10):2222-2227.
Published online October 1, 2003.
Corneal Edema Induced by Balafilcon A Contact Lens in Rabbits.
Kyu Mee Kay, Jong Wook Hong, Hyo Myung Kim
1Department of Ophthalmology, Kangbuk Samsung Hospital, Sungkyunkwan University College of Medicine, Korea.
2Department of Ophthalmology, Guro Hospital, Korea University College of Medicine, Korea. hongjw@kumc.or.kr
3Department of Ophthalmology, Anam Hospital, Korea University College of Medicine, Korea.
백색 가토에서 Balafilcon 재질 콘택트 렌즈에 의한 각막 부종
계규미 ( Gye Gyu Mi ) , 홍종욱 ( Hong Jong Ug ) , 김효명 ( Kim Hyo Myeong )
Abstract
PURPOSE
To compare the increase of corneal thickness by Balafilcon A (PureVision(R)) with that by HEMA hydrogel in rabbits. METHODS: 15 eyes of New Zealand white rabbits were divided into three groups. Each group was as follows: Group 1 recieved tasorraphy without contact lens insertion, group 2 had PureVision(R) lens insertion with tasorraphy and group 3 had New hypa day(R) lens insertion with tasorrhaphy. After anterior segment examination, tasorrhaphy was performed in group 1 and corneal thickness was measured at 24 and 48 hours. Five PureVision lenses were applied to left corneas of group 2 and transient tasorrhaphy was performed. After 24 and 48 hours, corneal thickness was measured. Same procedure was made in group 3 by applying five New hypa day(R) lenses on left eyes. Anterior segment was reexamined with slit lamp at 24 and 48 hours in all three groups. RESULTS: Baseline corneal thickness showed no statistical difference among three groups (p>0.05). At 24 hours, the corneal thickness of group 3 (New hypa day(R) lens inserted) increased significantly than that of the other groups (p<0.05). At 48 hours, the corneal thickness of group 2 and 3 increased significantly than group 1 (p<0.05), but there was no statistical difference between two groups (p>0.05). CONCLUSIONS: Balafilcon A contact lens which has high oxygen transmissibility of silicone with high water content of hydrogel, induce less corneal swelling than conventional extended wear contact lens, HEMA hydrogel in short-term period. However long-term evaluation about Balafilcon A contact lens is required to get more data on corneal swelling and complications after long-term wearing.
Key Words: Balafilcon A;Corneal edema;Hydrogel extended contact lens


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