Journal of the Korean Ophthalmological Society 1999;40(4):1036-1042.
Published online April 1, 1999.
Diagnostic Criteria, Its Sensitivity, and Specificity with the Confocal Scanning Laser Ophthalmoscope TopSSTM.
Gae Rang Kwon, Changwon Kee
Kwon`s Eye Clinic.
자동시신경유두분석기인 TopSS를 사용한 녹내장 진단기준 설정, 진단적 민감도 및 특이도
권계량(Gae Rang Kwon),기창원(Chang Won Kee)
Abstract
This study was conducted to establish glaucomatous diagnostic criteria and to investigate its sensitivity and specificity with the confocal scanning laser ophthalmoscope(TopSSTM) on the basis of the normal values of the optic disc parameters in previous study. Abnormal ratio of optic disc parameters were analysed in 80 primary open angle glaucoma eyes - the subjects were divided into three groups according to visual field defects, each group of mild, moderate, and severe. and then glaucomatous diagnostic critera was established. According to this diagnostic criteria, we calculated its sensitivity and specificity. We established the glaucomatous diagnostic criteria with high sensitive five parameters(1/2 depth area, C/D ratio, neuroretinal rim area(NRRA), volume above, and notching), the established criteria are 1) If NRRA is decreased, one of the four parameters is abnormal. 2) If NRRA is normal, notching and one of the other three parameters are abnormal. Notching was defined as decreased neuroretinal area at either 6 o/c or 12 o/c sector. With this criteria, the sensitivity was 89.7% in mild group and 100% in moderate and severe groups and the specificity was 89.1% in normal groups. This criteria showed high sensitivity and specificity in the diagnosis of glaucoma, so as to be useful in the early detection of glaucomatous spticdisc changes.
Key Words: Confocal scanning laser ophthalmoscope;Dianostic criteria;Optic disc parameter;Sensitivity;Specificity


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