The Difference in Graft Rejection between Two Corneal Preservation Methods(Moist Chamber vs Optisol).

Lee, Eui Tae; Myung, Yoon Won; Shin, Jeong Ah

Original Article

Journal of the Korean Ophthalmological Society 1998;39(7):1340-1344.
Published online July 1, 1998.

The Difference in Graft Rejection between Two Corneal Preservation Methods(Moist Chamber vs Optisol).

Eui Tae Lee, Yoon Won Myung, Jeong Ah Shin

Department of Ophthalmology, Catholic University, Medical College, Seoul, Korea.

각막보전 방법에 따른 이식편의 거부반응 차이

이의태(Eui Tae Lee),명윤원(Yoon Won Myong),신정아(Jeong Ah Shin)

Abstract

To know the difference in graft rejection after corneal transplantation between moist chamber and Optisol(Chiron Co. Irvine, CA, U.S.A.) as cornea preservation methods, we compared two groups involving 50 patients(71 eyes) who had undergone partially penetrating keratoplasty (PPKP) for the treatment of keratoconus or corneal dystrophy from 1991 to 1995. The graft rejection had occurred in 10 of 40 eyes(25%) in moist chamber group and 9 of 31 eyes(29%) in Optisol group, and the cases of permanent corneal opacity after rejection were 5 of 40 eyes(12.5%), 3 of 31 eyes(9.7%) respectively. No difference in the two groups was statistically significant(P<0.05). We found the fact that the difference did not exist in the results from graft rejection after PPKP using moist chamber method for short preservation period, or Optisol method for the relatively long period allowing serological and immunological screen test.

Key Words: Moist chamber;Optisol;Partially penetrating keratoplasty(PPKP);Graft rejection