Initial Mitomycin C Trabeculectomy in Young Patients.

Kim, Yong Yeon; Jung, Hai Ryun

Original Article

Journal of the Korean Ophthalmological Society 1997;38(3):424-429.
Published online March 1, 1997.

Initial Mitomycin C Trabeculectomy in Young Patients.

Yong Yeon Kim, Hai Ryun Jung

Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea.

젊은 환자에게 mitomycin C를 이용한 섬유주절제술

정해륜(Hai Ryun Jung),김용연(Yong Yeon Kim)

Abstract

Antimetabolites that inhibit postoperative fibroblast proliferation increases the success of glaucoma filtration surgery. However, the use of mitomycin C in young patients has not been extensively studied. The effectiveness of initialtrabeculectomy with mitomycin C or uncomplicated glaucoma in patients age 40 years or younger was evaluated in a consecutive series of 15 eyes of 10 patients. Thirteen eyes had juvenile primary open-angle glaucoma and 2 eyes had steroid induced glaucoma. Mitomycin C (0.002%) was applied for 2 to 4 minutes during the surgery. The success rate was evaluated with Kaplan-Meier analysis, and it was 78% at postoperative 9 months. Complications included postoperative hyphema(7 eyes), hypotony (2 eyes), and bleb-related endophthalmitis.

Key Words: Juvenile primary open-angle glaucoma;Mitomycin C;Trabe culectomy