| Changes in IOP and HIstopathology Following Contact Transscleral Cyclophotocoagulation with Diode Laser in High Tension Rabbit Eyes. |
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Chan Soo Park, Hee Bae Ahn, Hee Seong Yoon, Sae Heun Rho |
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Department of Ophthalmology, College of Medicine Dong-A University, Pusan, Korea. |
| "고안압 가토에서의 diode 레이저를 이용한 접촉적 경공막 모양체 광응고술에 따른 안압하강 및 조직학적 변화 " |
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박찬수(Chan Soo Park),안희배(Hee Bae Ahn),윤희성(Hee Seong Yoon),노세현(Sae Heun Rho) |
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| Abstract |
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We evaluated the acute and long term intraocular pressure(IOP) lowering effect of diode laser contact transscleral cyclophotocoagulation by applying G probe to argon laser induced high tension pigmented rabbits through the changes in IOP and histopathology. Eighteen eyes of 18 high tension pigmented rabbits were treated with diode laser contact transscleral cyclophotocoagulation (24-30 application) 0.5mm posterior to the limbus over 360degrees and the other eyes were used as controls. The rabbits were divided into 3 groups according to the energy levels of diode laser (1st group; 0.8J of energy, 2nd; 1.0J of energy, and 3rd; 1.2J of energy). There were mean decrease in IOP of 24.4%, 38.4%, and 38.7% in 1st, 2nd, and 3rd groups respectively during 5 weeks after tratment (p<0.05). After treatment, microendoscopic findings of the ciliary body revealed blenching in 1.0 and 1.2J groups. Light microscopy 1 day after treatment revealed coagulation necrosis of the pigmented and nonpigmented ciliary epithelium, congestion of vessels, thrombosis, and pigment dispersion in all energy groups, with destruction increasing in relation to power. Five weeks after treatment, atrophy and fibrosis of the ciliary nonpigmented and pigmented epithelium and stroma were observed in all groups. |
| Key Words:
Contact transscleral cyclophotocoagulation;Diode laser;Histo pathology;IOP |
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