Effect of Intense Regulated Pulse Light on Thickness of Tear Film Lipid Layer and Dry Eye Syndrome. |
Tae Young Gil, Gi Hyun Bae, Joo Young Kwag, Joo Hyun, Jin Seok Choi, Kyu Hong Pak, Sung Kun Chung |
1Department of Ophthalmology, SahmYook Medical Center, Seoul, Korea. 2Saevit Eye Hospital, Goyang, Korea. eyekun@gmail.com |
조절펄스광선조사가 눈물막 지질층 두께 및 안구건조증에 미치는 효과 |
길태영1⋅배지현1⋅곽주영2⋅현 주2⋅최진석2⋅박규홍2⋅정성근2 |
삼육서울병원 안과1, 새빛안과병원2 |
Correspondence:
Sung Kun Chung, Email: eyekun@gmail.com |
Received: 26 July 2018 • Revised: 10 September 2018 • Accepted: 27 November 2018 |
Abstract |
PURPOSE To evaluate the clinical effect of intense regulated pulse light (IRPL) and changes in tear film thickness in dry eye patients. METHODS: A retrospective study was conducted on 25 patients with Meibomian gland dysfunction who had subjective dry eye discomfort and whose tear film break-up time (TBUT) was < 10 seconds. All patients were treated with IRPL three times on days 1, 15, and 45. TBUT, Schirmer 1 test results, cornea staining score with fluorescein, ocular surface disease index (OSDI), and lipid layer thickness were measured and compared before and after the procedure. RESULTS: TBUT was significantly increased from 3.7 ± 1.2 s to 4.4 ± 2.1 s after IRPL (p = 0.03). Schirmer 1 test and cornea staining scores changed significantly (p < 0.01 and p = 0.01, respectively). OSDI also showed a statistically significant improvement from 39.5 ± 17.5 points to 30.4 ± 18.7 points (p = 0.01). However, no significant difference in lipid layer thickness was observed (p = 0.49). CONCLUSIONS: IRPL is an effective treatment modality to improve TBUT, Schirmer 1 test scores, cornea staining scores, and subjective dry eye symptoms. |
Key Words:
Dry eye syndrome;Intense pulse light (IPL);Intense regulated pulse light (IRPL);Lipid layer thickness (LLT);Lipiview |
|