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Regression of Neovascularization after Using Only Intraocular Pressure-lowering Medications in Neovascular Glaucoma
망막비허혈 신생혈관녹내장환자에서 안압하강치료만으로 신생혈관 소실
JKOS 2020 Mar;61(3):307-12
Published online March 15, 2020;
Copyright © 2020 The Korean Ophthalmological Society.
PDF Download Count: 38 / View Count: 30

Sang Wook Lee, MD, Ko Eun Kim, MD, PhD

Department of Ophthalmology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea
을지대학교 의과대학 노원을지대학교병원 안과학교실
Received June 20, 2019; Revised August 25, 2019; Accepted February 21, 2020.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: To report a case of neovascular glaucoma after intraocular lens iris fixation, in which the neovascularization of the iris and the anterior chamber improved with only intraocular pressure (IOP) lowering agents, without treatment of the underlying cause.
Case summary: A 74-year-old woman who had undergone bilateral cataract surgery presented with left ocular pain and headache that started 3 days previously. At the initial examination, the best-corrected visual acuity was 0.9, and the IOP was 38 mmHg in the left eye. Slit-lamp examination of the left eye revealed diffuse iris neovascularization and several polypropylene suture knots fixated in the superior and inferior iris. Gonioscopic examination revealed angle neovascularization in all quadrants, with focal peripheral anterior synechia in the inferior quadrant. Fundus examination presented inferior neuroretinal rim thinning and an inferior retinal nerve fiber layer defect in the left eye. Fluorescent angiography showed no ischemic retinal lesions, with the exception of several retinal microaneurysms. Six months after topical IOP-lowering treatment in the left eye, the IOP was 10 mmHg, and neovascularization of the iris and angle had regressed completely.
Conclusions: In the case of early-stage neovascular glaucoma with partial angle closure not associated with retinal ischemia, IOP-lowering treatment can be effective without other invasive procedures.
Keywords : Angle neovascularization, Intraocular lens fixation, Intraocular pressure-lowering medication, Iris neovascularization, Neovascular glaucoma


March 2020, 61 (3)