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An Unusual Case of Benign Episodic Bilateral Mydriasis
양안에서 발생한 양성 간헐동공산대 1예
JKOS 2019 Sep;60(9):901-4
Published online September 15, 2019;
Copyright © 2019 The Korean Ophthalmological Society.
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Ye Rim Ahn, MD1, Han Ul Kim, MD1, Yerim Kim, MD2, Youn Joo Choi, MD1
안예림1 · 김한얼1 · 김예림2 · 최연주1

Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine1, Seoul, Korea
Department of Neurology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine2, Seoul, Korea
한림대학교 의과대학 강동성심병원 안과학교실1, 한림대학교 의과대학 강동성심병원 신경과학교실2
Received March 14, 2019; Revised May 1, 2019; Accepted August 16, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: Although benign episodic mydriasis has been rarely reported worldwide, most of the reports so far have occurred in unilaterally. To report an unusual case of benign episodic bilateral mydriasis.
Case summary: Nineteen-year-old woman who presented with intermittent dilation of both pupils two months ago. She had difficulty on reading and doing tasks because of her visual blur. This symptom usually lasted for 1-2 hours, occurred once every 2-3 days, most frequently during stressful situations. Headaches and dizziness accompanied the eye symptoms, and her pupils were both 5 mm in a lighted room and both 7 mm in a dark room. All tests, including brain magnetic resonance imaging, showed no abnormal findings. We diagnosed her as benign episodic bilateral mydriasis. The frequency of her symptoms decreased during the university vacation period.
Conclusions: In the absence of ophthalmologic or neurologic abnormalities other than headaches in patients with transient mydriasis, benign episodic mydriasis should be considered as a differential diagnosis. Although benign episodic bilateral mydriasis has a unilateral predominance, for the first time the authors report that benign episodic mydriasis may occur in both eyes during same episode.
Keywords : Benign episodic mydriasis, Mydriasis, Pupil


February 2020, 61 (2)