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Clinical Characteristics and Prognosis of Endogenous Endophthalmitis in Western Gyeongsangnam-do
서부 경남지역 내인성 안내염의 임상양상과 예후
JKOS 2019 Sep;60(9):851-8
Published online September 15, 2019;  https://doi.org/10.3341/jkos.2019.60.9.851
Copyright © 2019 The Korean Ophthalmological Society.
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Ji-Seong Jeong, MD1, Min Ho Shin, MD2, Jin Seok Seo, MD1, Woong-Sun Yoo, MD1, Jong Moon Park, MD, PhD1,3, In Young Chung, MD, PhD1,3
정지성1 · 신민호2 · 서진석1 · 유웅선1 · 박종문1,3 · 정인영1,3

Department of Ophthalmology, Gyeongsang National University College of Medicine1, Jinju, Korea
Department of Ophthalmology, Chosun University College of Medicine2, Gwangju, Korea
Institute of Health Sciences, Gyeongsang National University3, Jinju, Korea
경상대학교 의과대학 안과학교실1, 조선대학교 의과대학 안과학교실2, 경상대학교 건강과학연구원3
Received January 3, 2019; Revised February 7, 2019; Accepted August 16, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Purpose: To investigate the clinical features and prognosis associated with endogenous endophthalmitis (EE) in western Gyeongsangnam-do over an 11-year period.
Methods: This study was a retrospective review of the medical records of 24 patients (33 eyes) who presented with endogenous endophthalmitis at the Gyeongsang National University Hospital from 2007 to 2017.
Results: The mean age of onset was 63.2 years, and 58.3% of the patients were men. Bilateral involvement was observed in nine patients (37.5%). Liver abscess (30.3%) and urinary tract infection (24.2%) were the most common extraocular sources of infection. Positive culture result was noted in 72.7% of the patients. The most common causative agents were gram-negative organisms (45.8%); the most commonly isolated microorganism was Klebsiella pneumoniae. Vitreous tapping and intravitreal antibiotic injection were performed in all patients; pars plana vitrectomy with intravitreal injection of antibiotics was performed in 12 eyes (36.4%). Enucleation and evisceration were performed in six eyes (18.2%). Initial visual acuity worse than hand motion was associated with a significantly worse visual outcome (p = 0.001).
Conclusions: In our study, EE showed a poor visual prognosis, irrespective of treatment. Poor initial visual acuity was predictive of poor visual outcome. Liver abscess and urinary tract infections were common extraocular sources of EE and K. pneumoniae was the most common causative organism.
Keywords : Endophthalmitis, Klebsiella, Prognosis, Liver abscess

 

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