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Clinical Aspects of Infectious Keratitis in Western Gyeongsangnamdo, Republic of Korea
서부 경남 지역의 감염각막염환자의 임상양상 변화
JKOS 2019 Aug;60(8):731-9
Published online August 15, 2019;
Copyright © 2019 The Korean Ophthalmological Society.
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Mi-Hwa Park, MD1,2, Woong-Sun Yoo, MD1,2,3, Gyu-Nam Kim, MD1,2,3, Yong-Wun Cho, MD1,2, Seong-Wook Seo, MD, PhD1,2,3, Seong-Jae Kim, MD, PhD1,2,3
박미화1,2 · 유웅선1,2,3 · 김규남1,2,3 · 조용운1,2 · 서성욱1,2,3 · 김성재1,2,3

Department of Ophthalmology, College of Medicine, Gyeongsang National University1, Jinju, Korea
Department of Ophthalmology, Gyeongsang National University Hospital2, Jinju, Korea
Institute of Health Sciences, Gyeongsang National University3, Jinju, Korea
경상대학교 의과대학 안과학교실1, 경상대학교병원 안과2, 경상대학교 건강과학연구원3
Received January 10, 2019; Revised April 1, 2019; Accepted July 18, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: We investigated the regional characteristics and trends in causative agents, clinical features, and antibiotic susceptibility in infectious keratitis in western Gyeongnam province.
Methods: This retrospective chart review included 551 eyes of 551 patients with infectious keratitis, who were referred to our center from January 2004 to December 2017. The period of this study was divided into two terms of 7 years before and after 2011 to analyze the changes in causative organisms and antibiotic susceptibilities and to investigate the clinical features and regional characteristics in western Gyeongnam province.
Results: The most common occupation among patients was farming; the mean time taken for initial treatment was 8.6 days. The culture positivity rate was 35.8%, the most commonly isolated microorganisms were Staphylococcus epidermidis (14.5%) for Gram-positive bacteria and Pseudomona aeruginosa (13.5%) for Gram-negative bacteria. The distribution of culture-positive organisms before and after 2011 did not show any significant difference, but the increase in resistance to second and third generation quinolones was significantly greater in Gram-positive bacteria after 2011. There was no significant difference in clinical characteristics before and after 2011, but the hospital stay duration and treatment needs were significantly reduced.
Conclusions: This was a large-scale study analyzing the clinical features of infectious keratitis in western Gyeognam province over a 14-year period. The results will help us understand the characteristics, microbiology, and community in infectious keratitis by analyzing patients referred to tertiary centers.
Keywords : Antibiotic, Keratitis, Western Gyeongnam


September 2019, 60 (9)