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Interocular Symmetry of Optical Coherence Tomography Angiography Parameters in Normal Eyes of Korean Adults
한국 성인의 정상안에서 빛간섭단층혈관조영술 측정치의 양안 대칭성
JKOS 2019 Jul;60(7):676-84
Published online July 15, 2019;
Copyright © 2019 The Korean Ophthalmological Society.
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Hye Jin Park, MD1, Hyung Bin Lim, MD1,2, Min Woo Lee, MD1, Young Joon Jo, MD, PhD1, Jung Yeul Kim, MD, PhD1

Department of Ophthalmology, Chungnam National University Hospital1, Daejeon, Korea
Department of Ophthalmology, Armed Forces Capital Hospital2, Seongnam, Korea
충남대학교 의과대학 안과학교실1, 국군수도병원 안과2
Received December 20, 2018; Revised February 18, 2019; Accepted June 19, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: To evaluate the interocular symmetry of microvascular parameters measured by optical coherence tomography angiography (OCTA) in normal eyes of Korean adults.
Methods: We retrospectively reviewed the retinal microvascular structure of 91 healthy Korean subjects (182 eyes). We used OCTA to measure the area of the foveal avascular zone (FAZ), vessel density (VD), and perfusion density (PD) in both eyes. Intraclass correlation coefficients (ICCs), coefficients of variation (CVs), and Pearson correlation coefficients were calculated to evaluate the extent of agreement and correlations between binocular OCTA measurements.
Results: Both eyes had similar microvascular characteristics: FAZ area (right eye: 0.31 ± 0.11 mm2, left eye: 0.30 ± 0.10 mm2, p = 0.98), FAZ perimeter (right eye: 2.35 ± 0.45 mm, left eye: 2.36 ± 0.39 mm, p = 0.86). VD 1-mm center (right eye: 9.42 ± 2.75, left eye: 9.14 ± 2.96, p = 0.163), full area (right eye: 19.94 ± 1.65, left eye: 19.72 ± 1.76, p = 0.285), and PD 1-mm center (right eye: 0.16 ± 0.05, left eye: 0.16 ± 0.05, p = 0.151), full area (right eye: 0.36 ± 0.03, left eye: 0.36 ± 0.04, p = 0.716). All ICC values were above 0.8 and all CVs below 10%.
Conclusions: The microvascular structure, as represented by the VD, PD, and FAZ area measured via OCTA, was bilaterally symmetric in normal eyes of Korean adults.
Keywords : Foveal avascular zone, Interocular symmetry, Microvascular parameters, Optical coherence tomography angiography


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