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Comparison of Central Corneal Thickness Measurements between Noncontact Specular Microscopy and Ultrasound Pachymetry
비접촉경면현미경과 초음파 각막두께측정계를 이용해 측정한 중심각막두께의 비교
JKOS 2019 Jul;60(7):635-42
Published online July 15, 2019;
Copyright © 2019 The Korean Ophthalmological Society.
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Kyoung Ohn, MD, Mee Yon Lee, MD, PhD, Young Chun Lee, MD, PhD, Hye Young Shin, MD, PhD
온 경⋅이미연⋅이영춘⋅신혜영

Department of Ophthalmology, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu, Korea
가톨릭대학교 의과대학 의정부성모병원 안과학교실
Received February 14, 2019; Revised March 23, 2019; Accepted June 25, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: We compared and analyzed central corneal thickness (CCT) measurements according to the corneal thickness obtained with noncontact specular microscopy (NCSM) and ultrasound pachymetry (USP).
Methods: CCT was measured in the order of NCSM and USP by a single optometrist in 120 eyes of 120 healthy subjects. The measurements were compared between the devices and the measurement agreements and correlations between the devices were analyzed. To determine if the measurements differed depending on the thickness of the cornea, the patients were divided into three tertile groups from the thinnest patient by CCT measurement using USP, and then the differences in CCT measured by the two devices were analyzed.
Results: The CCT measurements using NCSM and USP were 548.25 ± 4.64 μm and 533.09 ± 35.96 μm, respectively. NCSM measurements were found to be thicker, showing statistically significant differences between the measurements (p < 0.001). The two examinations showed a high degree of correlation (r = 0.878; p < 0.01). In the three groups, the differences in CCT measurements between NCSM and USP were 12.93 ± 21.88 μm, 16.85 ± 15.89 μm, and 15.70 ± 20.46 μm, respectively, but the differences between the three groups were not statistically significant (p = 0.655).
Conclusions: Our results show that although the differences in CCT measurements using NCSM and USP were consistent regardless of the corneal thickness, the CCT measurements by NCSM and USP were highly correlated.
Keywords : Central corneal thickness, Endothelial cell density, Noncontact specular microscopy, Ultrasound pachymetry


August 2019, 60 (8)