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Primary Intraocular T-cell Lymphoma
원발 안구 내 T세포 림프종
JKOS 2019 Jun;60(6):594-9
Published online June 15, 2019;
Copyright © 2019 The Korean Ophthalmological Society.
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Yong-Il Shin, MD1, Ju Mi Kim, MD1, Jong-Joo Lee, MD, PhD1, Jung-Yeul Kim, MD, PhD1, Jinman Kim, MD, PhD2, Young-Joon Jo, MD, PhD1

Department of Ophthalmology, Chungnam National University College of Medicine1, Daejeon, Korea
Department of Pathology, Chungnam National University College of Medicine2, Daejeon, Korea
충남대학교 의과대학 안과학교실1, 충남대학교 의과대학 병리학교실2
Received September 20, 2018; Revised November 6, 2018; Accepted May 16, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: Intraocular lymphoma can be divided into primary and secondary usually involving B-cell lymphoma. Intraocular T-cell lymphoma is mostly secondary lymphoma while primary intraocular T-cell lymphoma is extremely rare. We report a case of primary T-cell lymphoma.
Case summary: A 62-year-old male without any systemic disease presented with a floater in the right eye. A fundus examination showed multiple whitish retinal infiltrations in the right eye. Intraocular lymphoma was suspected, and systemic examination was performed, but all results were normal. During steroid treatment, previous lesions were enlarged, new lesions developed, and a diagnosis of primary T-cell lymphoma was made by diagnostic vitrectomy. Consecutive intravitreal injections of methotrexate were performed. After eight injections, the vitreous and retinal lesions improved but we decided to terminate the injections due to corneal epitheliopathy. The corneal epitheliopathy was recovered and the patient is currently undergoing periodic follow-ups without progression of the lesion.
Conclusions: Although intraocular T-cell lymphoma is a rare condition, this primary T-cell type should be considered when an intraocular lymphoma lesion is suspected.
Keywords : Corneal epitheliopathy, Methotrexate, Primary intraocular T-cell lymphoma


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