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Corneal Ulcer Caused by Corynebacterium macginleyi
코리네박테리움 맥긴레이 각막궤양
JKOS 2019 Jun;60(6):582-6
Published online June 15, 2019;
Copyright © 2019 The Korean Ophthalmological Society.
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So Ra Bang, MD1, Min Ahn, MD, PhD1,2,3, Nam Chun Cho, MD, PhD1,2,3, In Cheon You, MD, PhD1,2,3
방소라1·안 민1,2,3·조남천1,2,3·유인천1,2,3

Department of Ophthalmology, Chonbuk National University Medical School1, Jeonju, Korea
Research Institute of Clinical Medicine, Chonbuk National University2, Jeonju, Korea
Biomedical Research Institute, Chonbuk National University Hospital3, Jeonju, Korea
전북대학교 의학전문대학원 안과학교실1, 전북대학교 임상의학연구소2, 전북대학교병원 의생명연구원3
Received September 6, 2018; Revised October 25, 2018; Accepted May 17, 2019.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Purpose: To report a case of a Corynebacterium macginleyi-infected corneal ulcer of a patient who had been treated for conjunctivitis for more than 3 months.
Case summary: A 72-year-old female was transferred from a private ophthalmic clinic for evaluation of herpetic keratitis with progressive corneal edema and infiltration in the left eye. She had a history of conjunctival hyperemia and eyeball pain in her left eye 3 months prior to her visit. She was treated with levofloxacin eye drops and acyclovir ointment (Herpesid®, Samil, Co., Ltd. Seoul, Korea). On slit lamp examination, 5.4 × 4.0 mm corneal epithelial defects and stromal infiltrations were observed in the upper to central cornea, and endothelial keratic precipitates were found. Gram positive bacteria were detected on Gram staining and Corynebacterium macginleyi was identified on bacterial cultures from the conjunctiva and cornea. She was treated with topical vancomycin eye drops. After 3 months of treatment, the corneal ulcer was completely resolved, leaving mild superficial opacity on the cornea.
Conclusions: While Corynebacterium macginleyi, normal flora of the conjunctiva, is considered a major causative agent for conjunctivitis and blepharitis, Corynebacterium macginleyi should also be considered a possible cause of slowly progressive keratitis in patients with chronic conjunctivitis.
Keywords : Corynebacterium macginleyi, Conjunctivitis, Corneal ulcer, Normal flora of conjunctiva


October 2019, 60 (10)